.5/1 and 1/2 for the most part are comprised of the tightest PLO players. They may like to see a lot of flops, but they are playing their hands str8 forward. There will be some tight aggro players from time to time, but for the most part it is check call draws, pot out nuts, and never play back. If you do start playing very aggressive, you will see more and more calls pre flop. People will try the approach of "i'm going to try and hit a hand and make him pay for being over aggressive". Playing tight aggressive seems to be the best way to handle these types of players, and frequent c bets will eventually get some lighter calls.
2/4 and 3/6 Here, players move into the more tight aggressive approach. They run with the power poker game, waiting for premium hands and attacking when they get them. Players here will always c bet, often 2 barrel if they are getting just a call, and there will be a wider 3 bet range (although still very premium hands). Loose aggressive can really work at these limits, but be careful about the C bet range. Don't get caught with a check raise on the turn when you have a decent draw. Position is also paramount against tight aggressive players. A min raise on the button with 10864 against AAxx when you are deep could yield some insane implied odds, but playing that same hand oop against an intelligent opponent with AAxx offers much less upside.
5/10, 10/20 Here, there is a mix of the tight aggressive and loose aggressive styles. Some players try to run over the tables while others wait for optimal situations. This is where player tendencies, ranging, and styles have to be observed more carefully. At these limits, you have to adapt to each individual player and get a hold of what they are capable of. Do they bluff the Ace blocker for the flush? Do they bluff str8 blockers? Do they bluff the Qs blocker on a 3 spade board? Do they ever slow play? Do they ever slow play two streets? Three?
I often find that people who are successful at one limit have trouble moving up to higher limits because they do not adapt. Their method that might have worked very well at 1/2 is crushed at 3/6, and they get frustrated because they can't figure out why they are "running bad". Try playing different styles in a session. Min reraise a ton, call down the nuts oop for two streets, bluff without a blocker. Exploring new strategies and spots (if you can afford it) is a great way to practice adapting to higher limits.